Discover how sashimi plots simplify RNA-seq data analysis by visualizing gene splicing and expression patterns. Learn why these plots are essential tools in bioinformatics for understanding complex gene structures and alternative splicing events.

This diagram illustrates the concept of alternative splicing, a key biological process where exons and introns from a pre-mRNA are rearranged to produce different mRNA isoforms from the same gene. The figure shows a DNA strand with distinct colors used to differentiate between exons and introns. It highlights how the splicing process can result in multiple protein variants, contributing to gene expression regulation and protein diversity in eukaryotic organisms. Alternative splicing is crucial for understanding the complexity of the human genome and its role in various diseases, including cancer and neurodegenerative disorders.

Discover how NGS technology is transforming genomics research, covering key aspects like sequencing depth, read mapping, DNA fragmentation, and quality control in this in-depth guide.

Techniques are becoming increasingly expensive. The financial gap between industry research and academic grants is enormous. How much longer will academics be able to afford to perform research?

Here you can read more about the differences between bulk RNA-seq and scRNA-Seq, the benefits and disadvantages of scRNA-seq and what might be possible in the future. We will also briefly discuss the analysis of scRNA-Seq. How can scRNA-seq be used to study cell heterogeneity, cell type identification, cell state transitions or spatial transcriptomics.

The SPTAN1 gene carries instructions for making a membrane scaffolding protein called alpha-II spectrin. This protein is like a construction worker, helping to build and maintain the structure of our cells, especially in the brain. Think of it as the scaffolding that holds everything together.

Bisulfite sequencing is a powerful technique for studying RNA methylation patterns. In this article, we will explore bisulfite sequencing for RNA methylation research, explaining its principles, applications, and the insights it provides into the complex world of epitranscriptomics.

Stress Awareness Month is held every April to raise awareness about the impact of stress on our lives and to provide resources and tools to help individuals manage stress effectively.

Obesity and gut bacteria are closely linked. In this blog we discuss the possibility of bacterial transfer between lean and overweight people, the link between nutrition and gut bacteria, the effect of food supplements and tips for getting more good bacteria in the gut.

Oral mucositis is a condition where the lining of the mouth, throat, and gastrointestinal tract becomes inflamed and develops painful mouth sores or ulcers. Unfortunately, it is a common side effect of certain cancer treatments such as chemotherapy and radiation therapy.

Mutations in the TEFM gene cause mitochondrial disease. What does that mean? What does the TEFM gene do? How was NGS analysis used to study the role of this gene?

ChatGPT poem about International day of Women and Girls in Science. Every year on February 11 this day is an opportunity to celebrate and raise awareness of the important contributions of women to science and technology

What is rare disease day? What can we do on rare disease day? Are there any event happening near me?

What does ChatGTP write about mitochondrial diseases, MELAS, LHON, Leigh syndrome and mitochondrial myopathy?

Mitochondrial gene editing simply explained

What is next generation sequencing? Next gen sequencing vs Sanger. What are the different next gen sequencing steps?