Research areas

Our Core NGS Data Analysis Services

Cancer Genomics

Understanding the genomic landscape of cancer is critical for advancing diagnostics, treatment, and precision medicine. Our specialised NGS analysis services help researchers:

• Identify somatic mutations linked to cancer progression.

• Understand tumour heterogeneity and its implications on prognosis.

• Support the development of personalised treatment strategies based on molecular data.

Examples of NGS in cancer research are Identifying novel biomarkers, assessing responses to targeted therapies, and predicting disease outcomes. You can read more here.

Human genetics

Our comprehensive analysis of DNA sequencing enables researchers to explore:

• Genetic variations contribute to human health and disease.

• Genetic predispositions to various conditions.

• Complex traits that influence individual biological differences.

By unravelling the genomic intricacies, we assist in bridging the gap between genotype and phenotype.

Transcriptomics and alternative splicing

Gene expression analysis plays a vital role in understanding biological functions. Our RNA-Seq services provide insights into the following:

• Differential gene expression under various conditions.

• Identifying alternative splicing events that regulate gene function.

• Performing pathway analysis to understand complex biological systems.

Our transcriptomic services empower researchers to discover how gene expression patterns influence cellular behaviour and disease progression.
Read more about how bioinformatics aids gene expression analysis and alternative splicing analysis.

Microbiome studies

Uncover the hidden world of microorganisms with metagenomics analysis. Our services allow researchers to:

• Characterise microbial communities in environments ranging from the human body to ecosystems.

• Unveil the functional roles of the microbiome in health, disease, and environmental processes.

  See some examples of metagenomics studies here.

Drug development

Accelerate drug discovery with targeted genomic insights. Our NGS data analysis supports drug developers in:

• Identifying drug targets based on genomic data.

• Assessing drug efficacy and responses across different patient populations.

• Optimising therapeutic strategies for more precise and effective treatment outcomes.

Our services streamline the path to new therapies and more personalised medicine approaches by leveraging genomic data.

Gene editing (CRISPR/Cas9, ZFN, TALEN, DdCBE)

Stay ahead in the rapidly advancing field of gene editing with our specialised analysis services. We help researchers:

• Evaluate the efficiency of gene edits and detect off-target effects.

• Analyse genomic data to ensure precise outcomes in CRISPR/Cas9 or other gene-editing experiments.

Our bioinformatics solutions provide detailed insights into the precision and success of your gene editing research, contributing to advancements in genomic medicine.

Bioinformatics to check on- and off-target effects of gene editing

Mitochondrial research

Mitochondrial genomics is critical to understanding energy metabolism and various diseases. We offer NGS-based analysis for researchers to:

• Investigate mitochondrial disorders and their genetic basis.

• Explore the role of mitochondria in diseases such as cancer, neurodegeneration, and metabolic syndromes.

Our services contribute to breakthroughs in cellular bioenergetics and disease understanding by focusing on the mitochondrial genome.

Read more about NGS to study mitochondria.

Epigenomics and Epitranscriptomics

Explore the layers of genomic regulation through epigenomics and epitranscriptomics. Our services provide insights into:

• DNA methylation and histone modification patterns that regulate gene expression.

• RNA modifications that influence gene function post-transcriptionally.

By studying the epigenetic and epitranscriptomic mechanisms, researchers can uncover how external factors and cellular processes regulate the genome and affect biological outcomes.
Discover more about NGS in epigenomics and epitranscriptomics research.

Why Choose NextGenSeek?

At NextGenSeek, we understand the diverse and evolving needs of modern research. Our commitment to tailored solutions, cutting-edge technology, and expert knowledge ensures that researchers can extract the maximum value from their data. From genomics to epigenomics, our advanced analysis services are designed to push the boundaries of what’s possible.

Contact Us

Ready to transform your research with world-class NGS data analysis? Contact NextGenSeek today and collaborate with our team to advance your project.